When Covid-19 came into this world, we soon realized that the havoc wreaked by such a novel virus is due to the accumulation of inflammatory cytokines of which medical experts describe as " Cytokine Storm". This remains to be the prevailing theory up to this time and our local experience echos what has been observed. The presence of a persistent and unrelenting rise in measurable inflammatory cytokines among Covid-19 infected patients that is responsible for determining the overall clinical outcome.
After having seen quite a few Covid-19 infected patients, my view has changed. I look at “cytokine storm” as a misnomer because it seems to imply a sudden unpredictable surge in inflammatory levels. I prefer to describe Covid-19 infection as "an inflammatory condition associated with a progressive cytokine build-up". Our body compensates very well early on as these cytokines start building up but, it comes to a point when the body’s compensatory
mechanisms start to fail and clinically failure comes in two phases: